INternational observational study To Understand the impact and BEst practices of airway management in critically ill patients (INTUBE)

We are pleased to announce that INTUBE Study has been published in JAMA!

To read the primary analysis of INTUBE study click here
We are grateful to all investigators, colleagues and endorsing Societies for this amazing result!


Endorsed by:




INTUBE study is a large multi-centre, prospective, observational study on airway management in critically ill patients.


Tracheal intubation (TI) is a potentially life-threatening procedure for critically ill patients and major severe complications such as severe hypoxia, cardiovascular collapse and cardiac arrest are common.

This project aims to prospectively collect data on the current impact of TI-related adverse events and current airway management practice in critically ill patients.


We will prospectively collect data from 1000 TI-related major complications from at least 180 centres worldwide. Each center will be asked to collect data from 20 TIs.

Which patients?

All adult (≥ 18 year) critically ill patients undergoing in-hospital TI. We will exclude patients undergoing TI during cardiac arrest or anesthesia.


From 1 October to 3o April 2019 (with extra 8-week to complete enrollment if at a least a patient is already enrolled).

How do I participate?

We are looking for either academic or non-academic centres caring critically ill patients around the globe. Please register your interest here.


Supported by: